WP3: Validation of PACT treatment with Ru-MTI in orthotopic mice models

Objectives
  • O3.1 Validate orthotopic murine UM eye tumor and liver metastasis models
  • O3.2 Validate PACT treatment of UM with Ru-MTI in orthotopic mice models
  • O3.3 Study toxicity and eye toxicity of PACT treatment with Ru-MTI in healthy mice and in orthotopic mice tumor models